Get out of the medicine cabinet and reduce your risk of heart disease the natural way. A meta-review of a variety of studies and trials conducted by researchers in 2013 ­— encompassing 305 trials with more than 339,000 participants — found that no statistically detectable differences existed between those who exercised and those who were given medications in the prevention of coronary heart disease and prediabetes. (4)

Exercise has long been correlated with a longer life, but it’s only recently started to become clear why this might be. Studies, like a new one in the journal Preventive Medicine which found that exercise is linked to longer caps at the ends of chromosomes, have helped flesh this out a bit more. These caps, called telomeres, naturally shorten as we age, with each cell division. People who live a long time have telomeres that are in better shape than those who don’t—but there’s a lot we can do to affect the rate at which they shorten over the years. The team behind the new study looked at data from CDC's National Health and Nutrition Examination Survey, and found that for people who exercised regularly, their telomeres were 140 base pairs longer on average than sedentary people's. Which correlates to being years “younger” than their sedentary peers.

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